STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REM1RAS (RAD and GEM)-like GTP-binding 1. (292 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.863
ITSN1
Intersectin 1 (SH3 domain protein).
    
 0.765
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.732
SOS1
Uncharacterized protein.
    
 0.722
MLLT4
Myeloid/lymphoid or mixed-lineage leukemia translocated to, 4, transcript variant X12.
    
 
 0.715
GRB2
Growth factor receptor-bound protein 2.
   
 0.714
ZHX2
Zinc fingers and homeoboxes 2.
   
 0.701
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.686
G3BP1
GTPase activating protein (SH3 domain) binding protein 1.
    
 
 0.675
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.656
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.