STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (945 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
     
 0.916
GRB2
Growth factor receptor-bound protein 2.
   
 0.879
SOS1
Uncharacterized protein.
    
 0.838
BCAR1
Breast cancer anti-estrogen resistance 1.
    
 0.817
LPXN
Leupaxin.
    
 0.753
PXN
Paxillin, transcript variant X1; Belongs to the paxillin family.
    
 0.753
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
   
 0.742
YES1
Tyrosine-protein kinase.
   
0.742
SOS2
Uncharacterized protein.
    
 0.689
NEDD9
Neural cell expressed, developmentally down-regulated 9.
    
 0.668
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.