STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (597 aa)    
Predicted Functional Partners:
PRKN
E3 ubiquitin-protein ligase parkin.
    
 0.958
PINK1
PTEN induced putative kinase 1.
    
 0.957
WDR90
WD repeat domain 90.
 
 
 0.923
ITSN2
Intersectin 2.
    
 0.863
TRAK2
Trafficking protein, kinesin binding 2.
    
 0.796
ITSN1
Intersectin 1 (SH3 domain protein).
    
 0.765
TRAK1
Trafficking protein, kinesin binding 1, transcript variant X1.
    
 0.744
TOMM20
Uncharacterized protein.
   
 0.743
USP30
Ubiquitin carboxyl-terminal hydrolase.
     
 0.709
TOMM70
TPR_REGION domain-containing protein.
    
 0.708
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.