STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC25ACell division cycle 25A. (459 aa)    
Predicted Functional Partners:
CHEK1
Checkpoint kinase 1.
   
 0.994
PLK1
Polo-like kinase 1.
   
 0.988
CDK1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.987
CHEK2
Checkpoint kinase 2, transcript variant X1.
   
 0.986
CCNB3
Cyclin B3; Belongs to the cyclin family.
   
 0.978
CDK6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.974
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.973
CCNE1
Cyclin E1; Belongs to the cyclin family.
   
 0.972
CCNE2
Cyclin E2, transcript variant X3; Belongs to the cyclin family.
   
 0.972
CCND3
Cyclin D3; Belongs to the cyclin family.
   
 
 0.921
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.