STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IAPPIslet amyloid polypeptide. (86 aa)    
Predicted Functional Partners:
CALCR
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.993
CALCB
Calcitonin-related polypeptide beta, transcript variant X1.
     
 0.951
RAMP2
Receptor (G protein-coupled) activity modifying protein 2.
    
 0.946
RAMP3
Receptor (G protein-coupled) activity modifying protein 3.
    
 0.942
IDE
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.915
CALCRL
Calcitonin receptor-like; Belongs to the G-protein coupled receptor 2 family.
    
 0.809
NRD1
Nardilysin (N-arginine dibasic convertase); Belongs to the peptidase M16 family.
    
 
 0.669
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.607
CCK
Cholecystokinin.
  
  
 0.593
ADM
Adrenomedullin.
     
 0.570
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.