STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FECHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (487 aa)    
Predicted Functional Partners:
PPOX
Protoporphyrinogen oxidase.
  
 
 0.998
FXN
Frataxin, transcript variant X1.
    
 0.990
UROD
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 0.966
A306_00006448
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
   
 
 0.965
HMOX2
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
    
 0.958
HMOX1
Heme oxygenase 1.
    
 0.950
HEPH
Hephaestin, transcript variant X1; Belongs to the multicopper oxidase family.
   
 
 0.934
CP
Ceruloplasmin (Ferroxidase); Belongs to the multicopper oxidase family.
   
 
 0.931
A306_00005772
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
     
 0.920
ENDOV
Endonuclease V.
  
  
 0.890
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.