STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB27BRAB27B, member RAS oncogene family. (218 aa)    
Predicted Functional Partners:
A306_00007540
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.719
MADD
MAP-kinase activating death domain.
     
 0.701
GDI2
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
     
 0.663
SYTL4
Synaptotagmin-like 4.
   
 
 0.650
SYTL2
Synaptotagmin-like 2.
    
 
 0.632
A306_00007566
Synaptotagmin-like protein 2.
    
 
 0.632
A306_00000248
C2 domain-containing protein.
    
 
 0.627
MYO5B
Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.625
SYTL5
Synaptotagmin-like 5.
   
 
 0.613
PTAR1
Protein prenyltransferase alpha subunit repeat containing 1.
     
 0.613
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
Server load: low (30%) [HD]