STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOS1Uncharacterized protein. (1323 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
   
 0.999
EGFR
Receptor protein-tyrosine kinase.
    
 0.968
NRAS
Neuroblastoma RAS viral (V-ras) oncogene homolog.
   
 0.966
HRAS
Uncharacterized protein.
   
 0.966
KRAS
Uncharacterized protein.
   
 0.966
FGFR4
Fibroblast growth factor receptor.
    
 0.952
FGFR3
Fibroblast growth factor receptor.
    
 0.950
FGFR2
Fibroblast growth factor receptor.
    
 0.945
MRAS
Muscle RAS oncogene homolog, transcript variant X1.
    
 0.944
PDGFRB
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.943
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.