STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GDNFGlial cell derived neurotrophic factor, transcript variant X1. (218 aa)    
Predicted Functional Partners:
GFRA1
GDNF family receptor alpha; Belongs to the GDNFR family.
    
 0.969
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.955
GFRA2
GDNF family receptor alpha 2.
    
 0.905
GFRAL
GDNF family receptor alpha like.
    
 0.819
GFRA3
GDNF family receptor alpha 3.
    
 0.797
GFRA4
GDNF family receptor alpha 4.
     
 0.738
NTRK2
Tyrosine-protein kinase receptor.
     
 0.681
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.660
CNTF
Ciliary neurotrophic factor.
      
 0.657
ARTN
Artemin.
     
0.651
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.