STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A306_00010687Pancreatic secretory trypsin inhibitor. (85 aa)    
Predicted Functional Partners:
A306_00015345
Trypsin.
   
 0.569
A306_00000453
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.569
A306_00000410
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.569
A306_00015261
Kallikrein-13; Belongs to the peptidase S1 family.
   
 0.569
TMPRSS15
Transmembrane protease, serine 15; Belongs to the peptidase S1 family.
    
 0.528
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
      
 0.524
A306_00000412
Uncharacterized protein.
      
 0.475
A306_00009628
Chymotrypsinogen B; Belongs to the peptidase S1 family.
   
 0.455
PROC
Protein C (Inactivator of coagulation factors Va and VIIIa), transcript variant X1.
    
 0.408
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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