STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERN2Endoplasmic reticulum to nucleus signaling 2. (850 aa)    
Predicted Functional Partners:
XBP1
X-box binding protein 1.
    
 0.952
HSPA5
Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.
    
 0.941
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
   
0.937
ERN1
Endoplasmic reticulum to nucleus signaling 1, transcript variant X1.
  
  
 
0.902
ABCE1
ATP-binding cassette, sub-family E (OABP), member 1.
   
 0.674
SYVN1
E3 ubiquitin-protein ligase synoviolin.
    
 
 0.567
AMFR
Autocrine motility factor receptor, E3 ubiquitin protein ligase.
    
 
 0.567
SEC63
SEC63 homolog, protein translocation regulator.
    
 
 0.503
ITSN2
Intersectin 2.
   
 0.483
UBFD1
Ubiquitin family domain containing 1.
 
  
 0.477
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.