STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDH1BMalate dehydrogenase 1B, NAD (Soluble). (498 aa)    
Predicted Functional Partners:
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 0.827
FH
Fumarate hydratase.
  
 0.727
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.708
GOT2
Aspartate aminotransferase.
   
 0.683
ALDH18A1
Aldehyde dehydrogenase 18 family, member A1.
     
 0.678
DYTN
Dystrotelin.
 
    
 0.637
GAPDH
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.627
GOT1
Aspartate aminotransferase.
   
 0.624
SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 
 0.604
ACLY
ATP citrate lyase.
  
 0.603
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.