STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INPP5EInositol polyphosphate-5-phosphatase, 72 kDa. (656 aa)    
Predicted Functional Partners:
SACM1L
SAC domain-containing protein.
 
  
 0.990
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase, type I, beta.
     
 0.942
SYNJ1
Synaptojanin 1, transcript variant X2.
    
0.934
SYNJ2
Synaptojanin 2.
    
0.934
PIK3C2B
Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.
     
 0.919
PIK3C2A
Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.
     
 0.919
INPP5F
Phosphatidylinositide phosphatase SAC2.
 
   
 0.918
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma, transcript variant X1.
     
 0.915
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, transcript variant X1.
     
 0.915
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 
 0.913
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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