STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNCAIPSynuclein, alpha interacting protein. (965 aa)    
Predicted Functional Partners:
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 0.917
PRKN
E3 ubiquitin-protein ligase parkin.
    
 0.873
A306_00000615
RBR-type E3 ubiquitin transferase.
    
 0.873
SNCG
Gamma-synuclein; Belongs to the synuclein family.
    
 0.731
PLD1
Phospholipase.
   
 
 0.535
MC5R
Melanocortin 5 receptor, transcript variant X1.
    
 0.469
SH3BP5
SH3-domain binding protein 5 (BTK-associated).
    
 
 0.460
SIAH2
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.458
SIAH1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.458
NUB1
Negative regulator of ubiquitin-like proteins 1, transcript variant X1.
    
 0.440
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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