STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XPR1Xenotropic and polytropic retrovirus receptor 1. (665 aa)    
Predicted Functional Partners:
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
      
 0.661
NR1H4
Nuclear receptor subfamily 1, group H, member 4, transcript variant X1.
      
 0.657
PPARA
Peroxisome proliferator-activated receptor alpha, transcript variant X1.
      
 0.626
GPCPD1
Glycerophosphocholine phosphodiesterase 1.
      
 0.550
COL17A1
Collagen, type XVII, alpha 1.
      
 0.549
IP6K2
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.546
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5.
      
 0.537
KIDINS220
Kinase D-interacting substrate, 220kDa, transcript variant X1.
   
 
 0.534
SMPDL3B
XK-related protein.
      
 0.533
MYLIP
Myosin regulatory light chain interacting protein.
    
 
 0.531
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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