STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LEPRLeptin receptor. (889 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
    
 0.977
SOCS3
Suppressor of cytokine signaling 3.
    
 0.964
A306_00000141
Tyrosine-protein kinase.
    
 0.787
JAK1
Tyrosine-protein kinase.
    
 0.682
LEPROT
Leptin receptor overlapping transcript.
 
  
 
 0.639
TYK2
Tyrosine kinase 2.
    
 0.621
MC4R
Melanocortin 4 receptor.
      
 0.608
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.598
STAT3
Signal transducer and activator of transcription.
    
 0.587
POMC
Proopiomelanocortin.
      
 0.556
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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