STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKK3Dickkopf WNT signaling pathway inhibitor 3. (286 aa)    
Predicted Functional Partners:
DKK2
Dickkopf WNT signaling pathway inhibitor 2.
      
 0.751
LRP5
Low density lipoprotein receptor-related protein 5, transcript variant X2.
    
 0.610
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
      
 0.587
WNT6
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
     
 0.522
FZD10
Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.504
KREMEN1
Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.
    
 0.501
NFASC
Neurofascin.
      
 0.492
SFRP2
Secreted frizzled-related protein 2.
     
 0.491
NEGR1
Neuronal growth regulator 1.
   
 
 0.476
EDAR
Ectodysplasin A receptor, transcript variant X1.
      
 0.445
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.