STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XRCC3X-ray repair complementing defective repair in Chinese hamster cells 3. (347 aa)    
Predicted Functional Partners:
RAD51C
RAD51 paralog C.
  
0.992
A306_00013160
Werner syndrome ATP-dependent helicase-like.
  
 0.987
A306_00013159
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.987
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 
0.983
BRCA2
Breast cancer 2, early onset.
   
 0.964
RAD51D
RAD51 paralog D.
    
0.943
DMC1
DNA meiotic recombinase 1; Belongs to the RecA family.
  
0.942
RAD51B
RAD51 paralog B.
    
0.942
BLM
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.930
FBXO18
F-box protein, helicase, 18, transcript variant X1.
  
 
 0.923
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.