STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM2Isthmin 2. (478 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase, long chain base subunit 1.
 
 
 0.889
SORD
Sorbitol dehydrogenase.
  
 
 0.699
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.633
A306_00009442
Serine palmitoyltransferase small subunit B.
    
 0.614
ORMDL1
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.591
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.591
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
    
 0.575
ADHFE1
Alcohol dehydrogenase, iron containing, 1.
    
 0.528
BTBD3
BTB (POZ) domain containing 3, transcript variant X2.
      
 0.512
CCDC85C
Coiled-coil domain containing 85C.
      
 0.509
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.