STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HsdM-2DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)    
Predicted Functional Partners:
HsdS-2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
HsdR
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.971
HsdS
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.956
AQV01763.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.952
AQU99878.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.911
AQV01764.1
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.911
AQU99876.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.782
AQU99879.1
Cell filamentation protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.710
AQU99873.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.698
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.559
Your Current Organism:
Desulfococcus multivorans
NCBI taxonomy Id: 897
Other names: ATCC 33890, D. multivorans, DSM 2059, strain 1be1
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