Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aqpZAquaporin; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family. (229 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.911
GlpD
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.868
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.854
AQV02738.1
Rhomboid family intramembrane serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.822
AQV02819.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.813
TmcD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.812
AQV01817.1
Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.796
AQV01617.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.750
AQV02595.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.750
PpiA1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
   0.743
Your Current Organism:
Desulfococcus multivorans
NCBI taxonomy Id: 897
Other names: ATCC 33890, D. multivorans, DSM 2059, strain 1be1
Server load: low (10%) [HD]