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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQV02784.1Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)    
Predicted Functional Partners:
AQV02783.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.877
RpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.750
AQU99474.1
Chemotaxis protein CheR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.718
AQV01493.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.465
AQV01070.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.450
AQV02785.1
NosL family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.448
Your Current Organism:
Desulfococcus multivorans
NCBI taxonomy Id: 897
Other names: ATCC 33890, D. multivorans, DSM 2059, strain 1be1
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