Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRBReceptor-type tyrosine-protein phosphatase beta isoform X1. (1999 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.913
CDH5
Cadherin 5, type 2, VE-cadherin.
   
 0.824
ADGRF5
Adhesion G protein-coupled receptor F5.
   
 
 0.757
TEK
Endothelial-specific receptor tyrosine kinase.
   
 0.678
ITGA4
Integrin alpha-4 isoform X1.
  
 0.575
INPP1
Inositol polyphosphate 1-phosphatase.
      
 0.540
SLC25A12
Solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13.
      
 0.538
TP73
Tumor protein p73 isoform X1.
      
 0.536
TBC1D31
TBC1 domain family member 31 isoform X1.
      
 0.527
TIE1
Tyrosine-protein kinase receptor Tie-1 isoform X1.
   
 0.488
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.