STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSNMEP00000001529T-cell surface glycoprotein CD8 alpha chain-like. (276 aa)    
Predicted Functional Partners:
LOC110391409
Class I histocompatibility antigen, F10 alpha chain-like isoform X1.
    
 0.965
B2M
Beta-2-microglobulin.
   
 0.870
CD8B
T-cell surface glycoprotein CD8 beta chain isoform X1.
   
0.750
CD3E
T-cell surface glycoprotein CD3 epsilon chain.
   
 
 0.640
LCK
Lymphocyte cell-specific protein tyrosine kinase.
   
 
 0.613
CD247
T-cell surface glycoprotein CD3 zeta chain isoform X1.
   
 
 0.562
LOC110387606
T-cell surface glycoprotein CD3 gamma chain-like.
   
 0.538
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity).
   
  
 0.517
CD4
T-cell surface glycoprotein CD4 isoform X1.
   
 
 0.505
CD86
CD86 molecule.
   
  
 0.505
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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