STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR5E3 ubiquitin-protein ligase EDD1. (2829 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
  
0.905
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
 
 0.811
UBA52
Ubiquitin-60S ribosomal protein L40 isoform X1.
    
   0.705
UBC
Polyubiquitin-C isoform X1.
    
 
 0.669
PAIP1
Polyadenylate-binding protein-interacting protein 1 isoform X1.
   
   0.634
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1 isoform X1.
   
   0.634
EIF4G3
Eukaryotic translation initiation factor 4 gamma 3 isoform X1.
   
   0.594
USP34
Ubiquitin carboxyl-terminal hydrolase 34 isoform X1.
   
  
 0.578
EIF4G2
Eukaryotic translation initiation factor 4 gamma 2 isoform X1.
   
   0.556
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1 isoform X1.
    
   0.553
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.