STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLRP3NACHT, LRR and PYD domains-containing protein 3 isoform X1. (995 aa)    
Predicted Functional Partners:
ENSNMEP00000013941
Caspase-1-like.
   
 0.980
SUGT1
Suppressor of G2 allele of SKP1.
    
 0.946
MAVS
Mitochondrial antiviral-signaling protein isoform X1.
     
 0.938
HSP90AA1
Heat shock protein HSP 90-alpha.
    
 0.933
HSP90AB1
Heat shock protein HSP 90-beta.
    
 0.933
CTSB
Cathepsin B.
   
 
 0.913
ENSNMEP00000027001
Caspase recruitment domain-containing protein 8-like isoform X1.
    
 0.910
NFKB1
LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p105 subunit.
   
 
 0.902
IL1B
Interleukin-1 receptor antagonist protein-like.
   
 
 0.649
LOC110390481
Angiogenin-like.
    
 
 0.575
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.