STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP63Tumor protein 63 isoform X1. (685 aa)    
Predicted Functional Partners:
TP73
Tumor protein p73 isoform X1.
  
 
0.960
WRN
Werner syndrome ATP-dependent helicase isoform X1.
    
 0.830
MDM2
E3 ubiquitin-protein ligase Mdm2 isoform X1.
    
 0.793
ITCH
E3 ubiquitin-protein ligase Itchy homolog.
    
 0.775
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
 0.757
CHEK2
Serine/threonine-protein kinase Chk2 isoform X1.
    
 0.752
LOC110389170
Keratin, type II cytoskeletal 5-like.
   
 0.745
BARD1
BRCA1-associated RING domain protein 1 isoform X1.
    
 0.733
TP53BP1
Tumor suppressor p53-binding protein 1.
    
 
 0.702
LOC110389177
Keratin, type II cytoskeletal 8-like.
   
 0.701
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.