STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP2ADNA topoisomerase 2-alpha isoform X1. (1559 aa)    
Predicted Functional Partners:
TOP1
DNA topoisomerase I.
   
 
 0.833
UBE2C
Ubiquitin-conjugating enzyme E2 C.
   
 0.814
SMC2
Structural maintenance of chromosomes protein 2 isoform X1.
   
 
 0.802
CENPF
Centromere protein F isoform X1.
   
  
 0.778
KCTD9
Potassium channel tetramerization domain containing 9.
   
 
 0.761
TOP1MT
DNA topoisomerase I, mitochondrial isoform X1.
   
 
 0.752
NUSAP1
Nucleolar and spindle-associated protein 1 isoform X1.
   
  
 0.748
BIRC5
Baculoviral IAP repeat-containing protein 5 isoform X1.
   
  
 0.747
SUMO4
Small ubiquitin-related modifier 2.
    
 0.740
SMC4
Structural maintenance of chromosomes protein 4.
   
 
 0.739
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.