STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTK2BProtein-tyrosine kinase 2-beta isoform X1. (1033 aa)    
Predicted Functional Partners:
ITSN2
Intersectin-2 isoform X1.
     
 0.892
GRB2
Growth factor receptor-binding protein 2.
   
 0.885
SOS1
Son of sevenless homolog 1 isoform X1.
    
 0.852
BCAR1
Breast cancer anti-estrogen resistance protein 1-like.
    
 0.844
CASS4
Cas scaffolding protein family member 4 isoform X1.
    
 0.827
YES1
Tyrosine-protein kinase Yes.
   
0.808
SRC
Proto-oncogene tyrosine-protein kinase Src.
   
0.808
LPXN
Leupaxin isoform X1.
    
 0.798
PXN
Paxillin isoform X1.
    
 0.798
SOS2
Son of sevenless homolog 2 isoform X1.
    
 0.764
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.