STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZAP70Tyrosine-protein kinase ZAP-70. (596 aa)    
Predicted Functional Partners:
CD247
T-cell surface glycoprotein CD3 zeta chain isoform X1.
   
 0.993
CD3E
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.953
CBL
E3 ubiquitin-protein ligase CBL isoform X1.
    
 0.906
LCP2
Lymphocyte cytosolic protein 2.
   
 0.884
CD4
T-cell surface glycoprotein CD4 isoform X1.
   
 0.867
LCK
Lymphocyte cell-specific protein tyrosine kinase.
  
0.828
HCK
Tyrosine-protein kinase HCK isoform X1.
  
0.824
GRAP2
GRB2 related adaptor protein 2.
   
 0.817
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.810
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1.
   
0.799
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.