STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLKDNA polymerase kappa isoform X1. (867 aa)    
Predicted Functional Partners:
REV1
DNA repair protein REV1 isoform X1.
   
0.988
PCNA
Proliferating cell nuclear antigen.
   
 0.965
MAD2L2
Mitotic spindle assembly checkpoint protein MAD2B.
   
 0.941
WRN
Werner syndrome ATP-dependent helicase isoform X1.
  
 0.935
REV3L
DNA polymerase zeta catalytic subunit.
   
 0.913
POLE
DNA polymerase epsilon catalytic subunit A.
   
 0.839
POLH
DNA polymerase eta.
   
0.790
POLA1
DNA polymerase alpha catalytic subunit isoform X1.
   
 0.775
RAD51
DNA repair protein RAD51 homolog 1.
  
 0.769
POLD2
DNA polymerase delta subunit 2.
   
 0.744
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.