STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HACE1E3 ubiquitin-protein ligase HACE1 isoform X1. (942 aa)    
Predicted Functional Partners:
UBC
Polyubiquitin-C isoform X1.
   
 0.887
UBA52
Ubiquitin-60S ribosomal protein L40 isoform X1.
    
 0.824
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
 
0.764
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
   
 0.748
PRNP
Major prion protein homolog.
   
   0.744
MYCBP2
E3 ubiquitin-protein ligase MYCBP2 isoform X1.
   
 
 0.660
ALYREF
THO complex subunit 4.
    
 
 0.655
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1.
    
 
 0.651
DDIT4
DNA damage-inducible transcript 4 protein.
    
   0.651
ARHGAP6
Rho GTPase-activating protein 6 isoform X1.
      
 0.635
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.