STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOARas homolog gene family, member A. (193 aa)    
Predicted Functional Partners:
ROCK1
Rho-associated protein kinase 1 isoform X1.
   
 0.999
ITSN2
Intersectin-2 isoform X1.
    
 0.987
ROCK2
Rho-associated protein kinase 2 isoform X1.
   
 0.987
DAAM1
Disheveled-associated activator of morphogenesis 1.
    
 0.981
ARHGEF18
Rho guanine nucleotide exchange factor 18 isoform X1.
   
 0.978
ARHGAP35
Glucocorticoid receptor DNA-binding factor 1.
    
 0.974
PKN2
Serine/threonine-protein kinase N2 isoform X1.
   
 0.974
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 0.972
LOC110403650
Actin, cytoplasmic type 5.
   
 0.970
ARHGEF12
Rho guanine nucleotide exchange factor 12 isoform X1.
   
 0.970
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.