STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP3Caspase 3. (283 aa)    
Predicted Functional Partners:
XIAP
E3 ubiquitin-protein ligase XIAP.
   
 0.999
CASP8
Caspase-8-like.
  
0.995
LOC110403650
Actin, cytoplasmic type 5.
    
 0.989
BIRC2
Baculoviral IAP repeat-containing protein 2/3.
   
 0.987
CASP9
Caspase 9.
    
0.985
PARP1
Poly [ADP-ribose] polymerase 1 isoform X1.
   
 0.975
LOC110400694
Caspase-8-like.
   
0.970
BCL2
Apoptosis regulator Bcl-2.
   
 0.966
SPTAN1
Spectrin alpha chain, non-erythrocytic 1 isoform X1.
    
 0.966
APAF1
Apoptotic protease-activating factor 1 isoform X1.
    
 0.964
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.