STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNKSLOW QUALITY PROTEIN: tankyrase-1. (1262 aa)    
Predicted Functional Partners:
AXIN1
Axin-1 isoform X1.
    
 0.952
RNF146
E3 ubiquitin-protein ligase RNF146.
    
 0.943
AXIN2
Axin-2 isoform X1.
    
 0.924
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1.
    
 
 0.687
GMDS
GDP-mannose 4,6 dehydratase.
    
 
 0.649
PTEN
Phosphatase and tensin homolog.
   
 0.645
TNKS1BP1
182 kDa tankyrase-1-binding protein isoform X1.
    
 
 0.636
HIF1AN
Hypoxia-inducible factor 1-alpha inhibitor (HIF hydroxylase).
    
 
 0.629
BABAM1
BRISC and BRCA1-A complex member 1.
    
 0.612
LOC110388125
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like.
   
 0.610
Your Current Organism:
Numida meleagris
NCBI taxonomy Id: 8996
Other names: N. meleagris, helmeted guineafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.