| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFV72414.1 | SFV72416.1 | DESPIGER_0526 | DESPIGER_0528 | FIG00602688: hypothetical protein. | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | 0.759 |
| SFV72414.1 | SFV72417.1 | DESPIGER_0526 | DESPIGER_0529 | FIG00602688: hypothetical protein. | Siroheme synthase / Precorrin-2 oxidase. | 0.759 |
| SFV72414.1 | SFV72418.1 | DESPIGER_0526 | DESPIGER_0530 | FIG00602688: hypothetical protein. | FIG00604161: hypothetical protein. | 0.522 |
| SFV72414.1 | hemA | DESPIGER_0526 | DESPIGER_0527 | FIG00602688: hypothetical protein. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.789 |
| SFV72414.1 | tilS | DESPIGER_0526 | DESPIGER_0525 | FIG00602688: hypothetical protein. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.789 |
| SFV72416.1 | SFV72414.1 | DESPIGER_0528 | DESPIGER_0526 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | FIG00602688: hypothetical protein. | 0.759 |
| SFV72416.1 | SFV72417.1 | DESPIGER_0528 | DESPIGER_0529 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | Siroheme synthase / Precorrin-2 oxidase. | 0.789 |
| SFV72416.1 | SFV72418.1 | DESPIGER_0528 | DESPIGER_0530 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | FIG00604161: hypothetical protein. | 0.542 |
| SFV72416.1 | SFV72480.1 | DESPIGER_0528 | DESPIGER_0596 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | Thioredoxin family protein. | 0.412 |
| SFV72416.1 | SFV73128.1 | DESPIGER_0528 | DESPIGER_1278 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | Conserved hypothetical protein. | 0.402 |
| SFV72416.1 | SFV73595.1 | DESPIGER_0528 | DESPIGER_1763 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | ABC transporter involved in cytochrome c biogenesis, CcmB subunit. | 0.871 |
| SFV72416.1 | ccmE | DESPIGER_0528 | DESPIGER_1766 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | Cytochrome c-type biogenesis protein CcmE, heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. | 0.847 |
| SFV72416.1 | cobA | DESPIGER_0528 | DESPIGER_2025 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | Uroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase. | 0.775 |
| SFV72416.1 | hemA | DESPIGER_0528 | DESPIGER_0527 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.847 |
| SFV72416.1 | tilS | DESPIGER_0528 | DESPIGER_0525 | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.758 |
| SFV72417.1 | SFV72414.1 | DESPIGER_0529 | DESPIGER_0526 | Siroheme synthase / Precorrin-2 oxidase. | FIG00602688: hypothetical protein. | 0.759 |
| SFV72417.1 | SFV72416.1 | DESPIGER_0529 | DESPIGER_0528 | Siroheme synthase / Precorrin-2 oxidase. | HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase. | 0.789 |
| SFV72417.1 | SFV72418.1 | DESPIGER_0529 | DESPIGER_0530 | Siroheme synthase / Precorrin-2 oxidase. | FIG00604161: hypothetical protein. | 0.542 |
| SFV72417.1 | cobA | DESPIGER_0529 | DESPIGER_2025 | Siroheme synthase / Precorrin-2 oxidase. | Uroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase. | 0.998 |
| SFV72417.1 | hemA | DESPIGER_0529 | DESPIGER_0527 | Siroheme synthase / Precorrin-2 oxidase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.858 |