| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFV72744.1 | SFV72745.1 | DESPIGER_0875 | DESPIGER_0876 | HIT family protein. | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.731 |
| SFV72744.1 | xerC-2 | DESPIGER_0875 | DESPIGER_0877 | HIT family protein. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.702 |
| SFV72745.1 | SFV72744.1 | DESPIGER_0876 | DESPIGER_0875 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | HIT family protein. | 0.731 |
| SFV72745.1 | SFV72847.1 | DESPIGER_0876 | DESPIGER_0984 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Multi-sensor hybrid histidine kinase. | 0.815 |
| SFV72745.1 | coaE | DESPIGER_0876 | DESPIGER_0480 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Ribosomal large subunit pseudouridine synthase D; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.764 |
| SFV72745.1 | guaA | DESPIGER_0876 | DESPIGER_1027 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.914 |
| SFV72745.1 | guaB | DESPIGER_0876 | DESPIGER_1026 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.726 |
| SFV72745.1 | htpG | DESPIGER_0876 | DESPIGER_2139 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.738 |
| SFV72745.1 | infB | DESPIGER_0876 | DESPIGER_1712 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.725 |
| SFV72745.1 | ribA | DESPIGER_0876 | DESPIGER_2274 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.743 |
| SFV72745.1 | ribD | DESPIGER_0876 | DESPIGER_1075 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.846 |
| SFV72745.1 | xerC-2 | DESPIGER_0876 | DESPIGER_0877 | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.804 |
| SFV72847.1 | SFV72745.1 | DESPIGER_0984 | DESPIGER_0876 | Multi-sensor hybrid histidine kinase. | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.815 |
| SFV72847.1 | guaA | DESPIGER_0984 | DESPIGER_1027 | Multi-sensor hybrid histidine kinase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.748 |
| SFV72847.1 | guaB | DESPIGER_0984 | DESPIGER_1026 | Multi-sensor hybrid histidine kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.802 |
| SFV72847.1 | htpG | DESPIGER_0984 | DESPIGER_2139 | Multi-sensor hybrid histidine kinase. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.508 |
| SFV72847.1 | infB | DESPIGER_0984 | DESPIGER_1712 | Multi-sensor hybrid histidine kinase. | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.426 |
| SFV72847.1 | ribA | DESPIGER_0984 | DESPIGER_2274 | Multi-sensor hybrid histidine kinase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.680 |
| SFV72847.1 | ribD | DESPIGER_0984 | DESPIGER_1075 | Multi-sensor hybrid histidine kinase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.466 |
| coaE | SFV72745.1 | DESPIGER_0480 | DESPIGER_0876 | Ribosomal large subunit pseudouridine synthase D; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | tRNA nucleotidyltransferase, A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.764 |