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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypB[NiFe] hydrogenase nickel incorporation-associated protein HypB. (217 aa)    
Predicted Functional Partners:
hypA
[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.955
SFV74140.1
Ni,Fe-hydrogenase III large subunit.
   
 
 0.953
hypD
[NiFe] hydrogenase metallocenter assembly protein HypD; Belongs to the HypD family.
 
  
 0.940
hypA-2
[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.894
hypC
[NiFe] hydrogenase metallocenter assembly protein HypC.
 
  
 0.882
hypE
[NiFe] hydrogenase metallocenter assembly protein HypE.
 
  
 0.830
hypF
[NiFe] hydrogenase metallocenter assembly protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.801
SFV74025.1
Phosphosulfolactate synthase.
  
    0.730
SFV72375.1
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD.
    
 
 0.704
SFV72855.1
CoB--CoM-reducing hydrogenase (Sec) alpha subunit @ selenocysteine-containing.
 
  
 0.502
Your Current Organism:
Desulfovibrio piger
NCBI taxonomy Id: 901
Other names: ATCC 29098, D. piger, DSM 749, Desulfomonas pigra
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