| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFV72499.1 | SFV72500.1 | DESPIGER_0615 | DESPIGER_0616 | FIG00604054: hypothetical protein. | FIG00605471: hypothetical protein. | 0.982 |
| SFV72499.1 | gyrA | DESPIGER_0615 | DESPIGER_1855 | FIG00604054: hypothetical protein. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.621 |
| SFV72499.1 | rpoA | DESPIGER_0615 | DESPIGER_2568 | FIG00604054: hypothetical protein. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.791 |
| SFV72500.1 | SFV72499.1 | DESPIGER_0616 | DESPIGER_0615 | FIG00605471: hypothetical protein. | FIG00604054: hypothetical protein. | 0.982 |
| SFV72500.1 | gyrA | DESPIGER_0616 | DESPIGER_1855 | FIG00605471: hypothetical protein. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.621 |
| SFV72500.1 | rpoA | DESPIGER_0616 | DESPIGER_2568 | FIG00605471: hypothetical protein. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.784 |
| SFV72847.1 | dnaK | DESPIGER_0984 | DESPIGER_2258 | Multi-sensor hybrid histidine kinase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.619 |
| SFV72847.1 | dnaN | DESPIGER_0984 | DESPIGER_1852 | Multi-sensor hybrid histidine kinase. | DNA polymerase III beta subunit. | 0.728 |
| SFV72847.1 | ftsZ | DESPIGER_0984 | DESPIGER_0899 | Multi-sensor hybrid histidine kinase. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.564 |
| SFV72847.1 | gyrA | DESPIGER_0984 | DESPIGER_1855 | Multi-sensor hybrid histidine kinase. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.623 |
| SFV72847.1 | metG | DESPIGER_0984 | DESPIGER_0305 | Multi-sensor hybrid histidine kinase. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.589 |
| dnaK | SFV72847.1 | DESPIGER_2258 | DESPIGER_0984 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Multi-sensor hybrid histidine kinase. | 0.619 |
| dnaK | ftsZ | DESPIGER_2258 | DESPIGER_0899 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.422 |
| dnaK | gyrA | DESPIGER_2258 | DESPIGER_1855 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.589 |
| dnaK | gyrB | DESPIGER_2258 | DESPIGER_1853 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.535 |
| dnaK | metG | DESPIGER_2258 | DESPIGER_0305 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.477 |
| dnaK | rpoA | DESPIGER_2258 | DESPIGER_2568 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.606 |
| dnaN | SFV72847.1 | DESPIGER_1852 | DESPIGER_0984 | DNA polymerase III beta subunit. | Multi-sensor hybrid histidine kinase. | 0.728 |
| dnaN | gyrA | DESPIGER_1852 | DESPIGER_1855 | DNA polymerase III beta subunit. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.661 |
| dnaN | gyrB | DESPIGER_1852 | DESPIGER_1853 | DNA polymerase III beta subunit. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.916 |
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