STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobAUroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase. (505 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
SFV72417.1
Siroheme synthase / Precorrin-2 oxidase.
 
 0.998
hemB
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.989
cobI
Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.957
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.903
nifU
Iron-sulfur cluster assembly scaffold protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.885
cbiE
Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; Cobalt-precorrin-6y C5-methyltransferase / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating].
  
  
 0.838
hemL
Glutamate-1-semialdehyde aminotransferase.
 
  
 0.834
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
    0.821
pepA
Cytosol aminopeptidase PepA; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
       0.805
Your Current Organism:
Desulfovibrio piger
NCBI taxonomy Id: 901
Other names: ATCC 29098, D. piger, DSM 749, Desulfomonas pigra
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