SFV73931.1 protein (Desulfovibrio piger) - STRING interaction network

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Score

SFV73931.1

Serine acetyltransferase. (334 aa)

Predicted Functional Partners:

cysK

0.990

SFV73485.1

0.910

cysS

0.907

SFV73752.1

0.850

glyA

0.840

trpA

0.813

ilvA

0.812

trpB

0.807

trpB-2

0.807

pssA

0.801

Your Current Organism:

Desulfovibrio piger

NCBI taxonomy Id: 901
Other names: ATCC 29098, D. piger, DSM 749, Desulfomonas pigra

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFV73485.1	SFV73752.1	DESPIGER_1649	DESPIGER_1927	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Homoserine dehydrogenase.	0.821
SFV73485.1	SFV73931.1	DESPIGER_1649	DESPIGER_2109	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Serine acetyltransferase.	0.910
SFV73485.1	glyA	DESPIGER_1649	DESPIGER_1073	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.956
SFV73485.1	ilvA	DESPIGER_1649	DESPIGER_1171	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.928
SFV73485.1	pssA	DESPIGER_1649	DESPIGER_1551	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.900
SFV73485.1	trpA	DESPIGER_1649	DESPIGER_0494	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.901
SFV73485.1	trpB	DESPIGER_1649	DESPIGER_0493	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.900
SFV73485.1	trpB-2	DESPIGER_1649	DESPIGER_1352	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.900
SFV73752.1	SFV73485.1	DESPIGER_1927	DESPIGER_1649	Homoserine dehydrogenase.	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.821
SFV73752.1	SFV73931.1	DESPIGER_1927	DESPIGER_2109	Homoserine dehydrogenase.	Serine acetyltransferase.	0.850
SFV73752.1	ilvA	DESPIGER_1927	DESPIGER_1171	Homoserine dehydrogenase.	Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.502
SFV73931.1	SFV73485.1	DESPIGER_2109	DESPIGER_1649	Serine acetyltransferase.	L-serine dehydratase, beta subunit / L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.910
SFV73931.1	SFV73752.1	DESPIGER_2109	DESPIGER_1927	Serine acetyltransferase.	Homoserine dehydrogenase.	0.850
SFV73931.1	cysK	DESPIGER_2109	DESPIGER_1687	Serine acetyltransferase.	Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.990
SFV73931.1	cysS	DESPIGER_2109	DESPIGER_0590	Serine acetyltransferase.	Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.907
SFV73931.1	glyA	DESPIGER_2109	DESPIGER_1073	Serine acetyltransferase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.840
SFV73931.1	ilvA	DESPIGER_2109	DESPIGER_1171	Serine acetyltransferase.	Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.812
SFV73931.1	pssA	DESPIGER_2109	DESPIGER_1551	Serine acetyltransferase.	CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.801
SFV73931.1	trpA	DESPIGER_2109	DESPIGER_0494	Serine acetyltransferase.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.813
SFV73931.1	trpB	DESPIGER_2109	DESPIGER_0493	Serine acetyltransferase.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.807