| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFV74202.1 | SFV74204.1 | DESPIGER_2381 | DESPIGER_2383 | Hypothetical protein. | Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1); Belongs to the ABC transporter superfamily. | 0.773 |
| SFV74202.1 | cobT | DESPIGER_2381 | DESPIGER_2382 | Hypothetical protein. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.773 |
| SFV74204.1 | SFV74202.1 | DESPIGER_2383 | DESPIGER_2381 | Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1); Belongs to the ABC transporter superfamily. | Hypothetical protein. | 0.773 |
| SFV74204.1 | cobT | DESPIGER_2383 | DESPIGER_2382 | Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1); Belongs to the ABC transporter superfamily. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.776 |
| cbiA | cobB | DESPIGER_0952 | DESPIGER_2041 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyrinic acid A,C-diamide synthase. | 0.925 |
| cbiA | cobD | DESPIGER_0952 | DESPIGER_1558 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.838 |
| cbiA | cobH | DESPIGER_0952 | DESPIGER_0949 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalt-precorrin-8x methylmutase. | 0.995 |
| cbiA | cobI | DESPIGER_0952 | DESPIGER_0079 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.830 |
| cbiA | cobQ | DESPIGER_0952 | DESPIGER_0953 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.985 |
| cbiA | cobS | DESPIGER_0952 | DESPIGER_1559 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.807 |
| cbiA | cobT | DESPIGER_0952 | DESPIGER_2382 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.873 |
| cbiA | cobU | DESPIGER_0952 | DESPIGER_1560 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide kinase / Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.869 |
| cobB | cbiA | DESPIGER_2041 | DESPIGER_0952 | Cobyrinic acid A,C-diamide synthase. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.925 |
| cobB | cobD | DESPIGER_2041 | DESPIGER_1558 | Cobyrinic acid A,C-diamide synthase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.827 |
| cobB | cobH | DESPIGER_2041 | DESPIGER_0949 | Cobyrinic acid A,C-diamide synthase. | Cobalt-precorrin-8x methylmutase. | 0.985 |
| cobB | cobI | DESPIGER_2041 | DESPIGER_0079 | Cobyrinic acid A,C-diamide synthase. | Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.826 |
| cobB | cobQ | DESPIGER_2041 | DESPIGER_0953 | Cobyrinic acid A,C-diamide synthase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.931 |
| cobB | cobS | DESPIGER_2041 | DESPIGER_1559 | Cobyrinic acid A,C-diamide synthase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.788 |
| cobB | cobT | DESPIGER_2041 | DESPIGER_2382 | Cobyrinic acid A,C-diamide synthase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.816 |
| cobB | cobU | DESPIGER_2041 | DESPIGER_1560 | Cobyrinic acid A,C-diamide synthase. | Adenosylcobinamide kinase / Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.849 |