close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H355_014246SH2 domain-containing protein. (178 aa)    
Predicted Functional Partners:
H355_011140
Helicase C-terminal domain-containing protein.
    
 0.984
H355_007333
Uncharacterized protein.
   
 
 0.819
H355_000151
Uncharacterized protein.
    
 0.770
H355_008840
Tyrosine-protein kinase.
   
 0.765
H355_013262
Uncharacterized protein.
    
 0.738
H355_017058
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.708
H355_015086
Uncharacterized protein.
    
 0.708
H355_008480
Uncharacterized protein.
     
0.706
H355_007040
Uncharacterized protein.
    
 0.703
H355_005036
Uncharacterized protein.
    
  0.701
Your Current Organism:
Colinus virginianus
NCBI taxonomy Id: 9014
Other names: C. virginianus, bobwhite quail, common bobwhite, northern bobwhite
Server load: low (32%) [HD]