DOCK5 protein (Gallus gallus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Knowledge-based Evidence

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	CRK	ENSGALP00000065867	ENSGALP00000004174	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	0.568
CDC42	CRKL	ENSGALP00000065867	ENSGALP00000010305	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	CRK like proto-oncogene, adaptor protein.	0.426
CDC42	DOCK4	ENSGALP00000065867	ENSGALP00000066612	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Dedicator of cytokinesis 4; Belongs to the DOCK family.	0.740
CDC42	DOCK5	ENSGALP00000065867	ENSGALP00000000412	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.613
CDC42	RAC1	ENSGALP00000065867	ENSGALP00000011538	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	GTPase cRac1A.	0.878
CDC42	RHOG	ENSGALP00000065867	ENSGALP00000043362	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Ras homolog family member G.	0.594
CRK	CDC42	ENSGALP00000004174	ENSGALP00000065867	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	0.568
CRK	CRKL	ENSGALP00000004174	ENSGALP00000010305	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	CRK like proto-oncogene, adaptor protein.	0.994
CRK	DOCK4	ENSGALP00000004174	ENSGALP00000066612	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	Dedicator of cytokinesis 4; Belongs to the DOCK family.	0.516
CRK	DOCK5	ENSGALP00000004174	ENSGALP00000000412	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.764
CRK	ELMO3	ENSGALP00000004174	ENSGALP00000054619	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	ELMO domain-containing protein.	0.544
CRK	RAC1	ENSGALP00000004174	ENSGALP00000011538	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	GTPase cRac1A.	0.720
CRKL	CDC42	ENSGALP00000010305	ENSGALP00000065867	CRK like proto-oncogene, adaptor protein.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	0.426
CRKL	CRK	ENSGALP00000010305	ENSGALP00000004174	CRK like proto-oncogene, adaptor protein.	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	0.994
CRKL	DOCK4	ENSGALP00000010305	ENSGALP00000066612	CRK like proto-oncogene, adaptor protein.	Dedicator of cytokinesis 4; Belongs to the DOCK family.	0.577
CRKL	DOCK5	ENSGALP00000010305	ENSGALP00000000412	CRK like proto-oncogene, adaptor protein.	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.748
CRKL	ELMO3	ENSGALP00000010305	ENSGALP00000054619	CRK like proto-oncogene, adaptor protein.	ELMO domain-containing protein.	0.507
DOCK4	CDC42	ENSGALP00000066612	ENSGALP00000065867	Dedicator of cytokinesis 4; Belongs to the DOCK family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	0.740
DOCK4	CRK	ENSGALP00000066612	ENSGALP00000004174	Dedicator of cytokinesis 4; Belongs to the DOCK family.	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	0.516
DOCK4	CRKL	ENSGALP00000066612	ENSGALP00000010305	Dedicator of cytokinesis 4; Belongs to the DOCK family.	CRK like proto-oncogene, adaptor protein.	0.577