PIGR protein (Gallus gallus) - STRING interaction network

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Score

PIGR

Ig-like domain-containing protein. (648 aa)

Predicted Functional Partners:

JCHAIN

0.984

PIGA

0.882

HNRNPA2B1

0.636

IL10

0.607

PIGM

0.604

VILL

0.595

OVSTL

0.590

IL4

0.566

PTAFR

0.561

SLC25A44

0.540

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HNRNPA2B1	PIGR	ENSGALP00000056944	ENSGALP00000001351	Uncharacterized protein.	Ig-like domain-containing protein.	0.636
IL10	IL4	ENSGALP00000001310	ENSGALP00000039130	Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...]	Interleukin 4.	0.973
IL10	PIGR	ENSGALP00000001310	ENSGALP00000001351	Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...]	Ig-like domain-containing protein.	0.607
IL4	IL10	ENSGALP00000039130	ENSGALP00000001310	Interleukin 4.	Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...]	0.973
IL4	PIGR	ENSGALP00000039130	ENSGALP00000001351	Interleukin 4.	Ig-like domain-containing protein.	0.566
JCHAIN	PIGA	ENSGALP00000018817	ENSGALP00000026670	Uncharacterized protein.	Uncharacterized protein.	0.898
JCHAIN	PIGM	ENSGALP00000018817	ENSGALP00000037081	Uncharacterized protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity).	0.701
JCHAIN	PIGR	ENSGALP00000018817	ENSGALP00000001351	Uncharacterized protein.	Ig-like domain-containing protein.	0.984
OVSTL	PIGR	ENSGALP00000051424	ENSGALP00000001351	Uncharacterized protein.	Ig-like domain-containing protein.	0.590
PIGA	JCHAIN	ENSGALP00000026670	ENSGALP00000018817	Uncharacterized protein.	Uncharacterized protein.	0.898
PIGA	PIGM	ENSGALP00000026670	ENSGALP00000037081	Uncharacterized protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity).	0.933
PIGA	PIGR	ENSGALP00000026670	ENSGALP00000001351	Uncharacterized protein.	Ig-like domain-containing protein.	0.882
PIGM	JCHAIN	ENSGALP00000037081	ENSGALP00000018817	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity).	Uncharacterized protein.	0.701
PIGM	PIGA	ENSGALP00000037081	ENSGALP00000026670	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity).	Uncharacterized protein.	0.933
PIGM	PIGR	ENSGALP00000037081	ENSGALP00000001351	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity).	Ig-like domain-containing protein.	0.604
PIGR	HNRNPA2B1	ENSGALP00000001351	ENSGALP00000056944	Ig-like domain-containing protein.	Uncharacterized protein.	0.636
PIGR	IL10	ENSGALP00000001351	ENSGALP00000001310	Ig-like domain-containing protein.	Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...]	0.607
PIGR	IL4	ENSGALP00000001351	ENSGALP00000039130	Ig-like domain-containing protein.	Interleukin 4.	0.566
PIGR	JCHAIN	ENSGALP00000001351	ENSGALP00000018817	Ig-like domain-containing protein.	Uncharacterized protein.	0.984
PIGR	OVSTL	ENSGALP00000001351	ENSGALP00000051424	Ig-like domain-containing protein.	Uncharacterized protein.	0.590