STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM57Uncharacterized protein. (662 aa)    
Predicted Functional Partners:
SBNO1
Protein strawberry notch homolog 1; Belongs to the SBNO family.
   
  
 0.848
HAVCR1
Ig-like domain-containing protein.
   
  
 0.708
SIK3
SIK family kinase 3.
      
 0.705
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
      
 0.703
SEC62
Translocation protein SEC62; Required for preprotein translocation.
      
 0.672
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
      
 0.626
FAM174A
Family with sequence similarity 174 member A.
      
 0.601
TMEM50A
Transmembrane protein 50A.
 
    
 0.578
TTC26
Tetratricopeptide repeat domain 26.
      
 0.533
SYF2
Uncharacterized protein.
   
  
 0.531
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.