STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KBPProbable glutamate receptor; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (461 aa)    
Predicted Functional Partners:
GRIA1
Uncharacterized protein.
  
0.638
GRIN1
N-methyl-D-aspartate receptor type 1 subunit.
   
0.596
GRIA2
Uncharacterized protein.
  
0.595
GRIA3
Uncharacterized protein.
  
0.592
GRIK3
Glutamate ionotropic receptor kainate type subunit 3.
  
 
 
0.590
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
  
 
 
0.588
SCN2A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 
 0.582
GRIA4
Uncharacterized protein.
  
0.582
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
   
0.578
SCN3B
Sodium voltage-gated channel beta subunit 3.
   
 
  0.578
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.