node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADHFE1 | TBCD | ENSGALP00000054565 | ENSGALP00000002281 | Fe-ADH domain-containing protein. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.705 |
EPRS | FARSA | ENSGALP00000065180 | ENSGALP00000055258 | Uncharacterized protein. | Phenylalanine--tRNA ligase alpha subunit. | 0.892 |
EPRS | TBCD | ENSGALP00000065180 | ENSGALP00000002281 | Uncharacterized protein. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.673 |
FARSA | EPRS | ENSGALP00000055258 | ENSGALP00000065180 | Phenylalanine--tRNA ligase alpha subunit. | Uncharacterized protein. | 0.892 |
FARSA | TBCD | ENSGALP00000055258 | ENSGALP00000002281 | Phenylalanine--tRNA ligase alpha subunit. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.715 |
MMS19 | TBCD | ENSGALP00000012231 | ENSGALP00000002281 | MMS19 homolog, cytosolic iron-sulfur assembly component. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.645 |
PFDN4 | TBCD | ENSGALP00000012623 | ENSGALP00000002281 | Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.709 |
SMAP1 | TBCD | ENSGALP00000067066 | ENSGALP00000002281 | Small ArfGAP 1. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.772 |
TBCA | TBCB | ENSGALP00000072211 | ENSGALP00000066077 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway. | CAP-Gly domain-containing protein. | 0.893 |
TBCA | TBCC | ENSGALP00000072211 | ENSGALP00000069224 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway. | Tubulin folding cofactor C. | 0.532 |
TBCA | TBCD | ENSGALP00000072211 | ENSGALP00000002281 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.670 |
TBCA | TBCE | ENSGALP00000072211 | ENSGALP00000022566 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway. | Uncharacterized protein. | 0.941 |
TBCB | TBCA | ENSGALP00000066077 | ENSGALP00000072211 | CAP-Gly domain-containing protein. | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway. | 0.893 |
TBCB | TBCC | ENSGALP00000066077 | ENSGALP00000069224 | CAP-Gly domain-containing protein. | Tubulin folding cofactor C. | 0.626 |
TBCB | TBCD | ENSGALP00000066077 | ENSGALP00000002281 | CAP-Gly domain-containing protein. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.866 |
TBCB | TBCE | ENSGALP00000066077 | ENSGALP00000022566 | CAP-Gly domain-containing protein. | Uncharacterized protein. | 0.920 |
TBCC | TBCA | ENSGALP00000069224 | ENSGALP00000072211 | Tubulin folding cofactor C. | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway. | 0.532 |
TBCC | TBCB | ENSGALP00000069224 | ENSGALP00000066077 | Tubulin folding cofactor C. | CAP-Gly domain-containing protein. | 0.626 |
TBCC | TBCD | ENSGALP00000069224 | ENSGALP00000002281 | Tubulin folding cofactor C. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.674 |
TBCC | TBCE | ENSGALP00000069224 | ENSGALP00000022566 | Tubulin folding cofactor C. | Uncharacterized protein. | 0.674 |