STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTTG2Uncharacterized protein. (193 aa)    
Predicted Functional Partners:
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.999
CDC20
WD_REPEATS_REGION domain-containing protein.
   
 0.998
CDC27
Uncharacterized protein.
    
 0.978
CDK1
Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle (By similarity). It is required in higher cells for entry into S-phase and mitosis (By similarity). p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). May play a role in regulating the amplitude of the cyclic expression of circadian clock genes (By similarity). Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
   
  
 0.963
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.957
ANAPC2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
    
 0.945
CCNB1
G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition.
   
  
 0.941
UBE2C
Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.941
CDC16
TPR_REGION domain-containing protein.
   
 
 0.937
BUB1B
BUB1 N-terminal domain-containing protein.
   
 
 0.933
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.