node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APOA1 | APOA4 | ENSGALP00000011510 | ENSGALP00000071485 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Uncharacterized protein. | 0.858 |
APOA1 | APOV1 | ENSGALP00000011510 | ENSGALP00000024373 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | 0.879 |
APOA1 | LOC416959 | ENSGALP00000011510 | ENSGALP00000011051 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Ovotransferrin; Belongs to the transferrin family. | 0.527 |
APOA1 | MELTF | ENSGALP00000011510 | ENSGALP00000032783 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Ovotransferrin; Belongs to the transferrin family. | 0.531 |
APOA1 | VLDLR | ENSGALP00000011510 | ENSGALP00000073058 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). | 0.653 |
APOA1 | VTG2 | ENSGALP00000011510 | ENSGALP00000002888 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Lipovitellin-1; Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms. | 0.812 |
APOA4 | APOA1 | ENSGALP00000071485 | ENSGALP00000011510 | Uncharacterized protein. | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | 0.858 |
APOA4 | APOV1 | ENSGALP00000071485 | ENSGALP00000024373 | Uncharacterized protein. | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | 0.627 |
APOA4 | VLDLR | ENSGALP00000071485 | ENSGALP00000073058 | Uncharacterized protein. | Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). | 0.558 |
APOA4 | VTG2 | ENSGALP00000071485 | ENSGALP00000002888 | Uncharacterized protein. | Lipovitellin-1; Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms. | 0.644 |
APOV1 | APOA1 | ENSGALP00000024373 | ENSGALP00000011510 | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | 0.879 |
APOV1 | APOA4 | ENSGALP00000024373 | ENSGALP00000071485 | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | Uncharacterized protein. | 0.627 |
APOV1 | ESR1 | ENSGALP00000024373 | ENSGALP00000073938 | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.704 |
APOV1 | VLDLR | ENSGALP00000024373 | ENSGALP00000073058 | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). | 0.732 |
APOV1 | VTG2 | ENSGALP00000024373 | ENSGALP00000002888 | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | Lipovitellin-1; Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms. | 0.957 |
ESR1 | APOV1 | ENSGALP00000073938 | ENSGALP00000024373 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. | 0.704 |
ESR1 | VTG2 | ENSGALP00000073938 | ENSGALP00000002888 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Lipovitellin-1; Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms. | 0.721 |
LOC101749502 | LOC416959 | ENSGALP00000064757 | ENSGALP00000011051 | Uncharacterized protein. | Ovotransferrin; Belongs to the transferrin family. | 0.964 |
LOC101749502 | MELTF | ENSGALP00000064757 | ENSGALP00000032783 | Uncharacterized protein. | Ovotransferrin; Belongs to the transferrin family. | 0.951 |
LOC101749502 | VTG2 | ENSGALP00000064757 | ENSGALP00000002888 | Uncharacterized protein. | Lipovitellin-1; Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms. | 0.678 |